SS-31 (Elamipretide)

SS-31 is a four-residue peptide with an alternating aromatic-cationic structure that concentrates in the inner mitochondrial membrane. Crucially, that localisation appears largely independent of membrane potential — so unlike many cationic compounds, it reaches dysfunctional mitochondria too. Its target is cardiolipin, the four-tailed phospholipid that stabilises respiratory chain complexes and maintains cristae architecture.

SS-31 (Elamipretide) is a synthetic mitochondria-targeted research peptide referenced in laboratory studies of mitochondrial-membrane and bioenergetic signaling. It is used in controlled research models examining cardiolipin-association and electron-transport-chain mechanisms. Within preclinical frameworks, SS-31 is investigated for its mitochondrial-membrane-targeting profile and its role in studies of cellular-energetics and oxidative-stress pathways within controlled laboratory environments.

Strictly for in-vitro, cell-based, and preclinical laboratory research applications. No therapeutic, diagnostic, or clinical claims are made or implied.

• Mitochondrial-Membrane Studies — Investigation of cardiolipin-association and membrane-stability signaling in controlled models.
• Bioenergetics Research — Experimental study of electron-transport-chain and ATP-production signaling in preclinical systems.
• Oxidative-Stress Pathway Analysis — Research examining mitochondrial oxidative-stress-response pathways within laboratory frameworks.

What is SS-31 (Elamipretide) used for?
SS-31 is supplied for laboratory and preclinical research involving mitochondrial-membrane signaling and bioenergetic pathways. It is not intended for human or veterinary use, therapeutic application, or diagnostic purposes.

Who is eligible to purchase SS-31 (Elamipretide)?
SS-31 (Elamipretide) is sold exclusively to qualified researchers and licensed laboratories. By purchasing, buyers confirm they are knowledgeable in handling research-use-only (RUO) materials and will use the product in compliance with applicable regulations.

Is SS-31 (Elamipretide) approved for human or veterinary use?
No. This product is supplied strictly as a research material and is not approved for human or veterinary use, ingestion, diagnosis, or treatment of any condition.

What purity and quality standards are used?
Each batch is manufactured to high-purity standards and undergoes analytical verification and quality-control review. A batch-specific Certificate of Analysis (COA) is provided to document identity, purity, and applicable testing.

How should SS-31 (Elamipretide) be stored and handled?
It should be stored under controlled laboratory conditions, protected from heat, moisture, and direct light, and handled following standard laboratory protocols for research materials. Where applicable, avoid repeated freeze-thaw cycles.

Why does the vial appear nearly empty?
Research materials are supplied by analytical mass rather than visible volume. Contents may appear minimal within the container while still meeting the labeled specifications. This is normal for high-purity research materials.

Is documentation provided with each order?
Yes. Each batch is accompanied by a batch-specific Certificate of Analysis (COA) and supporting documentation to support quality assurance, batch traceability, and recordkeeping.

Can SS-31 (Elamipretide) be used in combination studies?
In laboratory settings, SS-31 (Elamipretide) may be evaluated alongside other research materials as part of structured experimental study designs. Any combination research should be conducted under controlled laboratory conditions and established analytical research protocols.

For laboratory and research use only. Not for human or veterinary use or consumption. Sold only to qualified researchers.

A Certificate of Analysis is issued for every lot and matched to the lot number printed on your vial. Identity is confirmed by mass spectrometry and purity by HPLC, with third-party ISO-accredited verification available on request. A Safety Data Sheet (SDS) is available for every product.

Orders are processed and shipped promptly via tracked courier. Materials ship lyophilized and remain stable in transit; on arrival, store as indicated on the vial — typically refrigerated or frozen and protected from light — for maximum stability.

See our Shipping & Returns policy for full details.